Endocrine Abstracts

The aim: To test cytotoxic effects of immune factors of patients with chronic diabetic foot ulcers on keratinocytes and fibroblasts in a 3D skin culture system.Materials and methods: In this study a multilayer 3D human skin model comprising of keratinocytes, fibroblasts and dendritic cells in an agarose-fibronectin gel was used. 20% serum of 13 patients with chronic noninfected diabetic foot ulcers, 13 diabetic type 2 patients and 13 healthy people and l...

According to the current expert recommendations it is advisable to screen microvascular complications: diabetic peripheral polyneuropathy (DPN), diabetic retinopathy (DR), diabetic nephropathy (DN) in all patients with type 1 diabetes mellitus (T1D) and disease duration of 5 years. Therefore, the aim of the study was to assess the clinical and laboratory parameters of patients with type 1 diabetes at the age of 30−45 years with duration of the disease 5–15 years, ta...

Background and aims: According to current recommendations of the American Diabetes Association expedient screening of microvascular complications in all patients with type 1 diabetes (T1D) with a duration of 5 years of the disease. Therefore, the aim of study was to assess the prevalence of microvascular complications in T1D patients aged 30−45 years with regard to the duration of the disease 5−10 years and over 10 years.Materials and methods...